What is Suboxone?
Firsly, Suboxone contains a combination of buprenorphine and naloxone. Buprenorphine is an opioid medication, sometimes called a narcotic. Buy suboxone online
Secondly, Naloxone blocks the effects of opioid medication, including pain relief or feelings of well-being that can lead to opioid abuse.
Suboxone is used to treat narcotic (opiate) addiction.
Suboxone is not for use as a pain medication.
Check with your doctor immediately if any of the following side effects occur while taking buprenorphine / naloxone:
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Firsly, To avoid precipitating an opioid withdrawal syndrome, the first dose of buprenorphine/naloxone should be started only when objective signs of moderate withdrawal appear.
Secondly, On Day 1, an induction dosage of up to 8 mg/2 mg SUBOXONE sublingual film is recommended.
In Additions, Clinicians should start with an initial dose of 2 mg/0.5 mg or 4 mg/1 mg buprenorphine/naloxone and may titrate upwards in 2 or 4 mg increments of buprenorphine, at approximately 2-hour intervals, under supervision, to 8 mg/2 mg buprenorphine/naloxone based on the control of acute withdrawal symptoms. Buy suboxone online
Moreover, On Day 2, a single daily dose of up to 16 mg/4 mg SUBOXONE sublingual film is recommended.
Above All, Because the exposure to naloxone is somewhat higher after buccal than after sublingual administration, it is recommended that the sublingual site of administration be used during induction to minimize exposure to naloxone, to reduce the risk of precipitated withdrawal.
Most Importantly, Buprenorphine/naloxone combination products have not been evaluated in adequate and well-controlled studies for induction in patients on long-acting opioid products, and contain naloxone, which is absorbed in small amounts by the sublingual route and could cause worse precipitated and prolonged withdrawal.
For this reason, buprenorphine monotherapy is recommended in patients taking long-acting opioids when used according to approved administration instructions.
However, Patients dependent on heroin or short-acting opioid products may be inducted with either SUBOXONE sublingual film or with sublingual buprenorphine monotherapy.
For example, The first dose of SUBOXONE sublingual film or buprenorphine should be administered when objective signs of moderate opioid withdrawal appear, and not less than 6 hours after the patient last used an opioid.
After treatment induction and stabilization, the maintenance dose of SUBOXONE sublingual film is generally in the range of 4 mg/1 mg buprenorphine/naloxone to 24 mg/6 mg buprenorphine/naloxone per day depending on the individual patient and clinical response.
Drug Interaction Classification
These classifications are only a guideline.
The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate: Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor: Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Suboxone Side Effects
- feeling faint, dizzy, or lightheaded
- feeling of warmth or heat
- flushing or redness of the skin, especially on the face and neck
- lower back or side pain
- painful or difficult urination
Incidence Not Known
- bloating or swelling of the face, arms, hands, lower legs, or feet
- darkening of the skin
- difficulty swallowing
- fast heartbeat
- hives, itching, skin rash
- loss of appetite
- mental depression
- overactive reflexes
- poor coordination
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rapid weight gain
- restlessness shivering talking or acting with excitement you cannot control tightness in the chest
- tingling of the hands or feet
- trembling or shaking twitching
- unusual weight gain or loss
Symptoms of Overdose
- Blurred vision
- difficult or troubled breathing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- irregular, fast, slow, or shallow breathing
- pale or blue lips, fingernails, or skin
- pinpoint pupils
- relaxed and calm feeling
- unusual tiredness or weakness
Some side effects of buprenorphine / naloxone may occur that usually do not need medical attention.
These side effects may go away during treatment as your body adjusts to the medicine.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Difficulty having a bowel movement
- lack or loss of strength
- stomach pain
- trouble sleeping
- Back pain
- runny nose
- stuffy nose
Incidence Not Known
- Burning or sore mouth
- burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings inside the mouth
- decline or loss of libido or sexual desire
- mood swings
- poor concentration
- redness, swelling, or soreness of the tongue
- reduced muscle strength
- swelling, inflammation, or redness of the mouth
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